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Colistin Methanesulfonate (sodium salt)

CAS No. 8068-28-8

Colistin Methanesulfonate (sodium salt)( —— )

Catalog No. M22759 CAS No. 8068-28-8

Colistin is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Colistin Methanesulfonate (sodium salt)
  • Note
    Research use only, not for human use.
  • Brief Description
    Colistin is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
  • Description
    Colistin is a cyclic polypeptide antibiotic from Bacillus colistinus, composed of Polymyxins E1 and E2.
  • In Vitro
    Colistin methanesulfonate is less bactericidal than colistin at the same multiples of the MIC. Colistin and colistin methanesulfonate are both unequal mixtures of the salts of two components, colistins A and B (1), which may well have different in vitro activities.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    Cell wall
  • Recptor
    cell wall
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    8068-28-8
  • Formula Weight
    1749.8
  • Molecular Formula
    C58H105N16Na5O28S5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 100 mg/mL
  • SMILES
    [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].CC(C)CCCCC(=O)N[C@@H](CCNCS([O-])(=O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCNCS([O-])(=O)=O)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCNCS([O-])(=O)=O)NC(=O)[C@H](CCNCS([O-])(=O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCNCS([O-])(=O)=O)NC1=O)[C@@H](C)O.CCC(C)CCCCC(=O)N[C@@H](CCNCS([O-])(=O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCNCS([O-])(=O)=O)C(=O)N[C@H]1CCNC(=O)[C@@H](NC(=O)[C@H](CCNCS([O-])(=O)=O)NC(=O)[C@H](CCNCS([O-])(=O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCNCS([O-])(=O)=O)NC1=O)[C@@H](C)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Evans ME, et al. Ann Pharmacother, 1999, 33(9), 960-967.
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